American Journal of Advanced Multidisciplinary Research and Innovation
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Volume 8 Issue 5
September-October 2026
Indexing Partners
AI-Driven Drug Discovery and Biomedical Innovation: Accelerating the Development of Next-Generation Healthcare Solutions
| Author(s) | Shon R. Hiatt |
|---|---|
| Country | United States |
| Abstract | Artificial Intelligence (AI) is transforming drug discovery and biomedical research by enabling researchers to analyse complex biological datasets, identify potential therapeutic targets, predict molecular properties, and accelerate the development of candidate drugs. Conventional drug discovery is often characterised by lengthy development cycles, high costs, substantial experimental requirements, and significant rates of clinical failure. AI-driven approaches offer opportunities to improve several stages of the pharmaceutical development pipeline, including target identification, molecular generation, virtual screening, drug–target interaction prediction, toxicity assessment, biomarker discovery, and clinical trial optimisation. This study examines the role of AI in drug discovery and biomedical innovation and evaluates its potential to accelerate the development of next-generation healthcare solutions. A qualitative and conceptual methodology based on secondary literature is adopted to examine AI applications across the drug-development lifecycle. The study proposes an integrated framework linking biological data, machine learning, generative AI, molecular modelling, experimental validation, and clinical translation. The analysis indicates that AI can reduce the search space for promising compounds, improve prediction capabilities, and support more personalised approaches to medicine. However, limitations involving data quality, model interpretability, biological complexity, algorithmic bias, reproducibility, intellectual property, regulatory uncertainty, and clinical validation remain significant. The study concludes that AI should be regarded as an augmentation technology that complements experimental science rather than a replacement for laboratory and clinical expertise. Successful AI-driven biomedical innovation will depend on high-quality data, multidisciplinary collaboration, transparent validation, responsible governance, and strong integration between computational prediction and experimental evidence. |
| Keywords | Artificial Intelligence, Drug Discovery, Biomedical Innovation, Machine Learning, Generative AI, Drug Development, Precision Medicine, Molecular Design, Healthcare Innovation, Computational Biology. |
| Field | Engineering |
| Published In | Volume 5, Issue 5, September-October 2023 |
| Published On | 2023-10-04 |
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E-ISSN XXXX-XXXXCrossRef DOI prefix of AJAMRI is 10.00000/AJAMRI
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